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Selectivity, accuracy and fast response are the challenges in current sensors; there is a huge requirement of more simplified designs. In this paper, we have designed and simulated MEMS based bio sensor for detecting Tuberculosis (TB) using FEM tool. Comparing with conventional techniques, the proposed design is more robust, reliable, price effective, very fast and highly sensitive. Two types of actuation...
This paper presents various aspects of a double gate field effect transistor based nano biosensor. It addresses the performance in detecting Human Epididymis Protein 4 (HE4) which is a key biomarker for detecting ovarian cancer. At first a double gate FET was designed and different parameters of HE4 protein was calculated. Various nano biosensor characteristics in terms of settling time, selectivity...
This study presents an integrated microfluidic system capable of rapid diagnosis and subtyping of influenza virus. Several critical modules including a ribonucleic acid (RNA) extraction module, a reverse-transcription polymerase chain reaction (RT-PCR) module and an optical detection module were integrated into the microsystem. Magnetic beads conjugated with specific nucleotide probes were first incubated...
Gateless AlGaN/GaN high electron mobility transistors (HEMTs) has some advantages include rapid response, low noise, and superior sensitivity. In different Al content, the Al0.3Ga0.7N has the excellent performance among Al0.17Ga0.83N and Al0.25Ga0.75N, and the performance can be achieved about -0.923 mA/mm-pH during pH 4-10, and -2.24 mA/mm-pH during pH 7-8. The result indicates that the better performance...
Liver segmentation on computed tomography (CT) images is a challenging task due to the anatomic complexity and the imaging system noise. In this paper, we develop an improved level set segmentation method. Our region-based level-set approach has many advantages over the conventional active contour models. First, the improved model can get much smoother contour by adding a signed distance preserving...
A new optical platform for the interrogation of a polymethylmethacrylate (PMMA) multichannel array for chemical and biochemical parameters is described. It consists of a plastic chip formed by two pieces of PMMA properly shaped in order to obtain different microchannels, 500 mum in width and 400 mum in height. A fluorescent sensing layer is immobilized on the internal wall of the microchannel. The...
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