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Rheumatoid arthritis (RHA) is one of the most prevalent complex, chronic, inflammatory diseases, manifested by elevated oxidative stress and inflammatory biomarkers. Prolonged administration of NSAIDs, steroids, and DMARDs, used in the treatment of RHA, is associated with deleterious side effects. This necessitates the urge of new and safe approaches for RHA management, based on the complementary...
Tomato foods contain bioactive compounds, such as lycopene, ascorbic acid and α-tocopherol, which are assumed to show synergistic effects. The aim of the study was to investigate this presumed synergy. The effect on lipid peroxidation and inflammation was assessed. Lipid peroxidation was effectively inhibited by combinations of the compounds compared to the single compounds. Synergy between the combination...
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