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Necrotic enteritis is a serious disease of chickens and turkeys caused by Clostridium perfringens. Recently, a pore forming toxin of C. perfringens, called NetB, was reported and suggested to be critical to the development of necrotic enteritis. To investigate further the importance of NetB in the development of necrotic enteritis, toxin production and disease producing ability of (1) netB positive...
Clostridium perfringens is a major enteric pathogen that is responsible for causing necrotic enteritis of poultry. The ability to adhere to the host’s intestinal epithelium and to extracellular matrix molecules (ECMM) in the gut, are strategies used by numerous bacterial enteropathogens, however, C. perfringens has received comparatively little attention in this respect. The present study investigated...
A previously unknown pore forming toxin, called NetB toxin, which is produced by some Australian strains of Clostridium perfringens has recently been reported. This toxin was reported to be critical to the development of the disease necrotic enteritis, in chickens. To investigate the occurrence of the toxin gene (netB) in non-Australian C. perfringens strains, one hundred and six American isolates...
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