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The emergence of drug‐resistant microbes left us with a great need for new antimicrobial agents. Flavonoids, with their wide range of biological activities, are good candidates in this respect. Although naturally occurring flavonoids are the most studied ones, semi‐synthetic or synthetic flavonoids have proven to have great potential, inhibiting and even killing microbes at concentrations below 1 ...
3-Hydroxy-2-aryl/heteroaryl-4H-chromones 4(a–n) were synthesized from appropriate chalcones 3(a–n) and acetylated to afford the corresponding acetoxy derivatives 5(a–n). All compounds were evaluated for antimicrobial activity against Staphylococus aureus, Bacillus subtillis, Escherichia coli and Pseudomonas aeruginosa as well as fungi e.g., Candida albicans and Aspergius niger. Inhibition caused by...
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