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The optical tweezer, with the ability to apply force and deformation on a micro scaled object on the order of piconewton (pN, 10~12 N) and nanometer (nm, 10~9 m), is utilized in this study to manipulate primitive myeloblasts from acute myeloid leukemia (AML) patients for biomechanical properties characterization. Mcrobeads are attached to cell surfaces serving as handles. Cells are stretched by moving...
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