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APOE ε4 carriers have thicker cortex in several neocortical areas than ε4 noncarriers (Espeseth T., Westlye L.T., Fjell A.M., Walhovd K.B., Rootwelt H., Reinvang I., 2008. Accelerated age-related cortical thinning in healthy carriers of apolipoprotein E ε4. Neurobiol. Aging 29, 329–340). To investigate potential physiological and cognitive correlates of these anatomical effects structural magnetic...
We examined the influence of APOE ε4 allele status on three cognitive outcomes in the same sample of 173 people: (i) IQ (Moray House Test) at age 11 years, (ii) IQ (Raven's Standard Progressive Matrices) at age 77 years, and (iii) change in IQ between age 11 and 77. All participants took part in the Scottish Mental Survey of 1932 and were followed-up in 1997-1998. There was no significant main effect...
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