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Mixed reality visualizations are increasingly studied for use in image guided surgery (IGS) systems, yet few mixed reality systems have been introduced for daily use into the operating room (OR). This may be the result of several factors: the systems are developed from a technical perspective, are rarely evaluated in the field, and/or lack consideration of the end user and the constraints of the OR...
Emotional learning involves two stages. The first is to acquire reinforcers from stimuli and the second is to associate such reinforcers with emotional responses. Both stages can be found occurring in the amygdala. LeDoux's fear circuit model suggests two routes, a subcortical route and a cortical route, for emotional information entering the amygdala for associative learning. It can be used to explain...
This study investigated whether manipulated visual feedback can affect neural activations while observing interactions in a virtual environment. Twelve healthy, right-handed subjects performed sequential finger flexions during functional MRI scanning. An MRI-compatible data glove was used to measure joint angles and to animate the movement of virtual hands in real time. Visual feedback of hand movement...
This paper proposes a parametric, multivariate method for the joint detection and segmentation of brain activation based on fMRI data. The proposed technique uses region based level sets to separate between the task-related and non-task-related regions and performs, at each iteration of level set evolution, a separate multivariate linear model (MLM) analysis in each of the two regions. Simulations...
We explore unsupervised, hypothesis-free methods for fMRI analysis in two different types of experiments. First, we employ clustering to identify large-scale functionally homogeneous systems. We formulate a generative mixture model, derive the EM algorithm and apply it to delineate functional systems. We also investigate spectral clustering in application to this problem and demonstrate that both...
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