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Many training simulators have been developed for use by surgeons to undertake surgical procedures in training. In several cases, the simulators are demanding of computer time, physical space and are costly. We have designed a low cost versatile simulator that can be used almost anywhere and on most computer systems. With modifications, it can be used with other thrombectomy devices. We simulate its...
Hemodynamics is believed to play a vital role in the initiation of cerebral aneurysms. In this study, we describe a newly defined hemodynamic quantity, the gradient oscillatory number (GON), as an index for the cerebral aneurysm initiation. It is defined by temporal variations of flow-induced tension/compression forces acting on endothelial cells. We calculated the index for the arterial geometry...
A modeling system is presented that can be used to predict the effects of ventilatory settings on the blood gases of patients on mechanical ventilation. The system uses a physiological model of the patient that includes lungs, body tissue, and brain tissue compartments. The model includes the effects of changes in the cardiac output and cerebral blood flow and lung mechanical factors. The system has...
The emerging functional MRI (magnetic resonance imaging), fMRI, imaging modality was developed to obtain non-invasive information regarding the neural processes behind pre-determined task. The data is gathered in such a way that the extraction certainty of the desired information is maximized. Still this is a difficult task due to low Signal-to-Noise Ratio (SNR), corrupting noise and artifacts from...
With the recent development, magnetic resonance imaging went beyond the anatomical and morphological imaging and gave information about physiological properties of the tissues. Anatomical images with high resolution could be get by MRI using a combination of rapid imaging techniques and bolus injection of extracellular contrast agents. Perfusion weighted MRI (PWI) has been used in clinical practices...
This research is aimed at integrating two-dimensional (2-D) optical topographic maps to anatomical magnetic resonance imaging (MRI) for 3-D functional brain mapping. The uniqueness of this approach is in mapping topographic maps to the cortex surface of the brain based on projections of the results obtained from the skull surface. MRI is known to provide information about the anatomical structure...
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