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Background Evidence suggests that variation in the length of the poly-C repeat in the 3′ untranslated region (3′UTR) of the β2-adrenergic receptor gene (ADRB2) may contribute to interindividual variation in β-agonist response. However, methodology in previous studies limited the assessment of the effect of sequence variation in the context of poly-C repeat length. The objectives of this study were...
All the components of the immune system involved in recognition and memory and in the nature, vigour and distribution of responses to antigenic challenge may be affected by the genotype and phenotype of the exposed person. They are likely to be greatly influenced by the individual genotype as well as by phenotype effects, and so are likely to vary greatly between individuals, depending on constitutional...
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