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From the seeds of Acacia confusa, a chitinase-like antifungal protein designated as acaconin that demonstrated antifungal activity toward Rhizoctonia solani with an IC50 of 30 ± 4 μM was isolated. Acaconin demonstrated an N-terminal sequence with pronounced similarity to chitinases and a molecular mass of 32 kDa. It was isolated by chromatography on Q-Sepharose, SP-Sepharose and Superdex 75 and was...
The effect of heparin sulphate on the infection of CD4+ lymphocytes by recombinant HIV-1 clones pIIIB and by pIIIB/V3-BaL was investigated. It was demonstrated that heparin sulphate decreased the infectivity of CD4+ lymphocytes by the pIIIB virus stronger than by the pIIIB/V3-BaL clone, and that the effect of heparin was concentration-dependent. This was accompanied by an inhibition of binding of...
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