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Over the recent years there has been a noticeable upsurge of interest in aza‐analogs of tryptophan which are isosteric to the latter and found numerous applications in medicinal, bioorganic chemistry, and peptide research. In the present review article, five aza‐tryptophan derivatives are profiled, including aza‐substitution in the positions 2, on the five‐membered ring, as well as in positions 4,...
In this review article, a detailed and comprehensive overview of the synthetic methods, discussion of the general facets of their biological properties, and most promising applications for five aza‐tryptophan derivatives, including aza‐substitution in positions 2, 4, 5, 6, and 7 were profiled. For more information, see the Review by Vadim A. Soloshonok et al. on page 17510 ff.
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