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The activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and concentrations of malondialdehyde (MAD) in serum, spleen and bursa of Fabricius and the concentrations of Immunoglobulin G (IgG) , Immunoglobulin A (IgA), Immunoglobulin M (IgM) and HI antibody titer to Newcastle Disease in serum were detected in chickens with different levels sub-chronic aluminum (Al) intoxication produced...
The model chicks was produced by continuous peritoneal injection of different concentration aluminium trichloride to investigate the effect of aluminum (Al) on calcium homeostasis in chicken brain at doses of Al3+ 0, 18.31, 27.47 and 36.62mg/kg BW/d lasting 60 days. The content of Al in brain tissues was measured by atomic absorption spectroscopy. The concentration of [Ca2+]i in fowl nerve cells was...
Idiosyncratic drug hepatotoxicity is a hepatotoxicity subset that occurs in a very small fraction of human patients, is poorly predicted by standard preclinical models and in clinical trials, and frequently leads to postapproval drug failure. Animal models utilizing bacterial LPS co-administration to induce an inflammatory background and hepatocyte cell culture models utilizing cytokine mix cotreatment...
In order to understand the characteristics of Stx2-converting bacteriophage and its role in stx virulence factor transmission between different E. coli strains, Stx2 bacteriophages were isolated from Shiga toxin-producing E. coli 0157 isolates of animal origin and phage characteristics were investigated. Three different virion morphologies of the purified phages were observed. All the Stx2 phages...
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