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2-Alkoxy-3-cyano-4,6-diarylpyridines 1a,b which were synthesized by condensation of α,β-unsaturated ketones with malononitrils were subjected to Lewis acid-catalyzed nucleophilic displacement reaction with various amines to afford the corresponding 2-aminopyridines 3–21. The potency of the results as antibacterial agents has been evaluated. The structure of the newly prepared compounds was assessed...
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