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Aims
β‐amyloid (Aβ) aggregation and deposition play a central role in the pathogenic process of Alzheimer's disease (AD). α‐Mangostin (α‐M), a polyphenolic xanthone, have been shown to dissociate Aβ oligomers. In this study, we further investigated the effect of α‐M on Aβ production and its molecular mechanism.
Methods
The Aβ and soluble amyloid precursor protein α (sAPPα) in culture medium of...
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