The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Previous studies with the malaria vaccine RTS,S/AS02 A in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce the risk of Plasmodium falciparum infection and disease.In this study, we assessed the antibody responses to the P. falciparum and hepatitis B components of the RTS,S/AS02 A vaccine over a 45months surveillance...
In a phase 1 trial, 22 children in a malaria endemic area were immunised with candidate malaria vaccination regimes. The regimes used two recombinant viral vectors, attenuated fowlpox strain FP9 and modified vaccinia virus Ankara (MVA). Both encoded the pre-erythrocytic malaria antigen construct ME–TRAP. Strong T cell responses were detected by both ex vivo and cultured ELISpot assays.Data from phase...
Does the RTS,S/AS02A vaccine reduce the incidence of malaria and clinical event rates in young children with malaria?Double blind randomised controlled trial.In young African children, the RTS,S/AS02A vaccine reduced malarial infections and clinical disease compared with control 6 months after vaccination (see results table).The RTS,S/AS02A vaccine was safe, well tolerated, and immunogenic.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.