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Though human pain imaging studies almost always demonstrate activation in the cerebellum, the role of the cerebellum in pain function is not well understood. Here we present results from two studies on the effects of noxious thermal heat and brush applied to the right side of the face in a group of healthy subjects (Group I) and a group of patients with neuropathic pain (Group II) who are more sensitive...
This paper considers the physiological mechanisms which contribute to clinical pain by describing how the pain (nociceptive) system changes its sensitivity depending upon the body's needs. The time-course of physiological events following an injury is described to show that the healthy nociceptive system is not a hard-wired pain pathway but rather a dynamic system which can change its state of activity...
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