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Experiments have been carried out to investigate the chemical substrate in the rostral ventrolateral medulla (RVLM) underlying the depressor responses induced by activation of the greater splanchnic nerve (GSPL) afferent fibres of the rat. In anaesthetised rats with urethane and alpha-chloralose, microinjection of bicuculline, a GABA A receptor antagonist, into the RVLM, attenuated largely...
We examined the effects of caloric vestibular stimulation on the neuronal activity of the locus coeruleus (LC) in urethane-anesthetized rats. The middle ear cavity was irrigated with hot (44°C) or cold (30°C) water through a polyethylene tube. Most neurons (hot water: 76%, 55; cold water: 90%, 19) exhibited suppression of neuronal discharge in response to caloric stimulation. The suppression of...
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