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In vivo preventive effects of a Mangifera indica L extract (Vimang) or its major component mangiferin on iron overload injury have been studied in rats given respectively, 50, 100, 250mgkg −1 body weight of Vimang, or 40mgkg −1 body weight of mangiferin, for 7days prior to, and for 7days following the administration of toxic amounts of iron-dextran. Both Vimang or mangiferin treatment...
A standard aqueous stem bark extract from selected species of Mangifera indica L. (Anacardiaceae)—Vimang, whose major polyphenolic component is mangiferin, displays potent in vitro and in vivo antioxidant activity. The present study provides evidence that the Vimang–Fe(III) mixture is more effective at scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radicals, as well as in protecting...
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