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It has been proposed that epigenetic modulation plays a critical role in cellular senescence and organismal aging. Two major epigenetic codes are DNA methylation and histone modifications, including acetylation, methylation, phosphorylation and ubiquitylation. Environmental factors such as dietary components can regulate gene expression by altering epigenetic modifications and may thus have long lasting...
Although there has been considerable interest in the aging process for quite some time and in epigenetics for over two decades, it is relatively recent that we have witnessed a surge in interest in aging epigenetics. Epigenetic processes are vast and influence many genes and other processes related to aging that impact the physiological decline that characterizes the aging process. This ranges from...
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