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This paper describes the in vitro effects of titanium dioxide (TiO 2 ) nanoparticles (NPs) upon human neutrophils. Kinetic experiments revealed no cell necrosis after 24h of treatment with TiO 2 (0–100μg/ml). In contrast, TiO 2 -induced change in cellular morphology in a concentration-dependent manner in neutrophils over time, indicating its potential to activate these cells...
We purified a neutrophil chemotactic factor from a culture fluid of the PHA-activated human T-cell leukemia SKW-3 cells. The factor showed a 16-kDa basic protein by Tricin-SDS-polyacrylamide gel electrophoresis and analysis of amino acid composition. The primary amino acid sequence revealed that the chemotactic factor was significantly different from other known chemotactic factors, indicating a...
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