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Summary Cardiac involvement can be found in all types of amyloidosis, but is most frequent in AL amyloidosis. Severity of cardiac infiltration is by far the most relevant prognostic determinant. Once the heart is affected, amyloidosis carries a poor prognosis. Diagnosis is based on non-invasive testing such as ECG, echocardiography and cardiac MRI (CMR). However, endomyocardial biopsy is needed to...
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