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. Objective: We investigated the potential use and action mechanisms of thiazolidinedione (TZD) agonists for peroxisome proliferator-activated receptor-γ, namely pioglitazone and netoglitazone, during dextran sulfate sodium (DSS)-induced colitis in mice. Methods: Colitis was induced by the drinking of 2.5% DSS for 7 days. In the prophylactic protocol, pioglitazone or netoglitazone was administered...
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