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Penetration enhancers coated biodegradable polymeric nanogels loaded with cytotoxic drugs applied via the topical route, can be a promising strategy for improving the chemotherapeutic efficiency of skin cancers. The major objective of proposed research was to investigate the in vitro and ex vivo chemotherapeutic potential of double walled PLGA-chitosan biodegradable nanogel entrapped with 5-fluororuacil...
Rosmarinic acid (RA) is a naturally occurring phenolic compound with antioxidant, anti-carcinogenic and anti-inflammatory activities, amongst others, and is therefore a compound of interest for cosmetic applications. However RA instability, poor solubility in water and low partition coefficient constrain its transport across biological barriers, the inclusion in a cosmetic formulation and the efficacy...
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