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Using high content analysis (HCA), we assessed whether cytotoxicity biomarkers translate from in vitro to in vivo models using four anti-cancer drugs (arabinoside C, arsenic trioxide, doxorubicin, and mitoxantrone) and staining live cells with Hoechst 33342 for DNA (nuclear area, nuclear intensity and cell number), Fluo-4 for ionised calcium, TMRM for mitochondrial membrane potential and TOTO-3 for...
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