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Copper of exogenous origin is present in crab hemolymph mainly in a protein-bound form. Various approaches were used to assess the toxicity of this protein-bound exogenous metal. Mortality due to copper directly injected into the hemolymph space was apparent at circulating concentrations of non-hemocyanic copper much higher than that (about 150 μM) attained during exposure to a lethal level of waterborne...
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