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Recruitment of osteoblast lineage cells to their bone-forming locations is essential for skeletal development and fracture healing. In developing bones, osteoprogenitor cells invade the cartilage mold to establish the primary ossification center. Similarly, osteogenic cells infiltrate and populate the callus tissue that is formed following an injury. Proper bone development and successful fracture...
Die Rekrutierung von Zellen der Osteoblastenlinie an den Ort der Knochenbildung ist wesentlich für die skeletale Entwicklung und Frakturheilung. In sich entwickelnden Knochen wandern Osteoprogenitorzellen in das Knorpelgewebe ein und bilden dort das primäre Ossifikationszentrum. In ähnlicher Weise infiltrieren und besiedeln osteogene Zellen das Kallusgewebe, das nach einer Verletzung gebildet wird...
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