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Background and Purpose
Resting‐state functional MRI (rs‐fMRI) studies in Parkinson's disease (PD) patients with freezing of gait (FOG) have implicated dysfunctional connectivity over multiple resting‐state networks (RSNs). While these findings provided network‐specific insights and information related to the aberrant or altered regional functional connectivity (FC), whether these alterations have...
Aims
This study aimed to characterize the topological alterations and classification performance of high‐order functional connectivity (HOFC) networks in cognitively preserved patients with Parkinson's disease (PD), relative to low‐order FC (LOFC) networks.
Methods
The topological metrics of the constructed networks (LOFC and HOFC) obtained from fifty‐one cognitively normal patients with PD and...
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