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Reasons for performing studyHypoxia‐inducible factor‐1α (HIF‐1A) is an important protein in the regulation/induction of many genes in the cellular and tissue response to hypoxia and a central mediator in inflammatory signalling. As both hypoxia and inflammatory events are purported to occur in the lamellar epidermis in sepsis‐related laminitis in the equid, HIF‐1A may play a central role in this disease...
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