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To evaluate paclitaxel/carboplatin in a dose dense (TCdd) and weekly (TCw) regimen in recurrent or primary metastatic cervical cancer.Six courses of paclitaxel (90mg/m 2 ) and carboplatin (area under the curve (AUC) 4) were administered on d1, d8 q3 wks in TCdd. Eighteen courses of paclitaxel (60mg/m 2 ) and carboplatin (AUC 2.7) were administered weekly in TCw. Response rates were...
The combination of Carboplatin and Paclitaxel is considered the standard of care as initial chemotherapy for Advanced Ovarian Cancer (AOC). We compared this regimen with the combination of Cisplatin, Paclitaxel and Doxorubicin.Patients with AOC were randomised to either six courses of Paclitaxel 175mg/m 2 plus Carboplatin 7AUC or Paclitaxel at the same dose plus Cisplatin 75mg/m 2 ...
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