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Ergebnisse der Grundlagenforschung haben in den vergangenen 2 Jahrzehnten die molekulare Heterogenität von Tumorerkrankungen aufgezeigt. Durch die Entwicklung neuer Technologien in den letzten 5 bis 10 Jahren war es möglich, eine Vielzahl von krebsauslösenden Veränderungen im Genom von Tumorzellen zu beschreiben, die letztlich zur malignen Transformation normaler Zellen führen. Die bisher meistens...
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