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Blast-injured patients routinely challenge the orthopedic surgeons and other who care for them. Although they have been traditionally associated with combat and military medicine, recent events have demonstrated that civilian surgeons must be prepared to deal with these complex patients and associated injury patterns. Moreover, surgeons must anticipate the most common complications that afflict blast...
New strategies for the care of irritable bowel syndrome (IBS) are developing and several novel treatments have been globally produced. New methods of care should be customized geographically because each country has a specific medical system, life style, eating habit, gut microbiota, genes and so on. Several clinical guidelines for IBS have been proposed and the Japanese Society of Gastroenterology...
This review provides an historical perspective on events that have shaped our pathophysiological understanding of sepsis during this century and, as a result, have influenced the design of glucocorticoid treatment trials. A structured format to evaluate clinical investigation of glucocorticoid treatment in patients with sepsis is presented. From the early 1950s to the late 1980s, the methodological...
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