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The genomics efforts have identified a large number of novel genes and thus provided a pool of interesting but not functionally characterized target proteins. It has been suggested that structural proteomics will significantly impact the success rate of functional characterization of such identified genes and proteins by providing structure-function hypotheses by fold and feature recognition and analysis...
The major challenge for post-genomic research is to functionally assign and validate a large number of novel target genes and their corresponding proteins. Functional genomics approaches have, therefore, gained considerable attention in the quest to convert this massive data set into useful information. One of the crucial components for the functional understanding of unassigned proteins is the analysis...
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