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The study was aimed at the investigation of the rat corticospinal system both functionally and anatomically using as a functional marker the immediate early gene c-fos, combined with retrograde tracing with horseradish peroxidase (HRP). This was achieved by mapping c-fos induction immunocytochemically in the spinal cord as a result of occlusion of the middle cerebral artery (MCA). Following left-sided...
This study is a sequel of our previous work which demonstrated the expression of Fos-like immunoreactivity (Fos-LI) in the spinal cord motoneurons of rat following permanent occlusion of the middle cerebral artery (MCA). We report here Fos-LI in the hypothalamic, medullary and thoracic spinal cord neurons some of them are believed to be involved in cardiovascular regulation after the cerebral ischaemic...
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