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Les mutations du gene p53 representent l'alteration genetique la plus frequente dans les tumeurs malignes. P21 qui est un inhibiteur des kinases-dependantes des cyclines est le mediateur privilegie de l'arret du cycle cellulaire medie par p53. Bien que de nombreuses etudes aient ete consacrees aux mutations et a l'expression de p53 dans les cancers coliques, peu de travaux ont realise une etude conjointe...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.