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HO‐3867, a synthetic curcumin analog, has displayed various tumor‐suppressive characteristics and improved bioabsorption over its parent compound. However, its influences on the development of hepatocellular carcinoma (HCC) are poorly defined. To address this, we tested the anticarcinogenic impact of HO‐3867 and investigated the underlying mechanisms in fighting liver cancer. Our result demonstrated...
Curcumin‐based structural modification for developing more effective curcumin analogues has been drawning increasing attention. As alternative approach, using LC/MS guided purification, we previously obtained a series of novel natural terpene‐conjugated curcuminoids from turmeric, and some of them exhibited even more potent anti‐cancer activity against multiple types of cancer cells than curcumin...
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