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The glucose transporters GLUT-1 and GLUT-3 are targets of the hypoxia-inducible transcription factor HIF-1α and it has been shown that nucleus pulposus (NP) cells in rat intervertebral discs (IVD) express both HIF-1α and GLUT-1. However, there is limited data on the expression of HIF-1α and GLUTs in human IVD. The aim here was to (1) determine whether, like articular chondrocytes, human IVD cells...
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