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Objective
This study was undertaken to develop a multimodal machine learning (ML) approach for predicting incident depression in adults with epilepsy.
Methods
We randomly selected 200 patients from the Calgary Comprehensive Epilepsy Program registry and linked their registry‐based clinical data to their first‐available clinical electroencephalogram (EEG) and magnetic resonance imaging (MRI) study...
Magnetoencephalography with optically pumped magnometers (OPM‐MEG) is an emerging and novel, cost‐effective wearable system that can simultaneously record neuronal activity with high temporal resolution ("when" neuronal activity occurs) and spatial resolution ("where" neuronal activity occurs). This paper will first outline recent methodological advances in OPM‐MEG compared to...
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are brain regions with high connectivity to other parts of the brain and are typically situated along the brain's most efficient communication pathways, supporting large‐scale brain wiring and many higher order neural functions...
Objective
To identify magnetic resonance imaging (MRI) biomarkers for post‐traumatic epilepsy.
Methods
The EPITARGET (Targets and biomarkers for antiepileptogenesis, epitarget.eu) animal cohort completing T2 relaxation and diffusion tensor MRI follow‐up and 1‐month‐long video‐electroencephalography monitoring included 98 male Sprague‐Dawley rats with traumatic brain injury and 18 controls. T2 imaging...
Objective
To increase the diagnostic power of scalp electroencephalography (EEG) by investigating whether lesion type and location influence the morphology of interictal epileptic discharges (IEDs) and the likelihood that IEDs and high‐frequency oscillations (HFOs) are present.
Methods
We studied EEG activity in epilepsy patients with lesional epilepsy. Lesions were classified by type and by location...
PurposeTo evaluate the usefulness of ictal electroencephalography (EEG)–combined functional magnetic resonance imaging ( MRI) (EEG‐fMRI) in localizing epileptogenic zone in refractory neocortical focal epilepsy.
MethodsFrom the EEG‐fMRI database of our institution including 62 adult patients, 14 (age 18–46 years) experienced some ictal event during the test. Data were segmented into 10‐s blocks,...
Purpose: In patients with drug‐refractory focal epilepsy, nonlesional magnetic resonance imaging (MRI) or discordant data of presurgical standard investigations leads to failure generating a sufficient hypothesis for electrode implantation or epilepsy surgery. The seizure‐onset zone can be further investigated by subtraction ictal single‐photon emission computed tomography (SPECT) coregistered to...
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