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We describe the morphology of a zebrafish strain which lacks pelvic fins but no other abnormalities. This description is the first step of analyzing hindlimb loss in an established model organism. By combining light microscopy, bone and cartilage staining, scanning electron microscopy and histological sections we were able to comprehensively describe the morphology of the developing pelvic fins of...
Zebrafish fins have a proximal skeleton of endochondral bones and a distal skeleton of dermal bones. Recent experimental and genetic studies are discovering mechanisms to control fin skeleton morphogenesis. Whereas the endochondral skeleton has been extensively studied, the formation of the dermal skeleton requires further revision. The shape of the dermal skeleton of the fin is generated in its distal...
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