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Virus-like particles (VLPs) are of interest in vaccination, gene therapy and drug delivery. Their assembly process needs to be understood in order to improve their yield and quality. Triple-layered Rotavirus-like particle (TLP 2/6/7), a candidate vaccine against Rotavirus infection, is produced in insect cells by co-infection of baculoviruses coding for VP2, VP6 and VP7, the main structural proteins...
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