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Breast cancer is the second most common cancer in women, but chemotherapy and targeting antibodies possess certain side effects. Today’s efforts are aimed to search of new effective methods of breast cancer treatment, especially triple-negative breast cancer, which cannot be affected by conventional therapeutics. Binase, the RNase secreted by Bacillus pumilus, possesses unusual biological activities...
Endogenous growth factors and cytokines are known to have a major influence on the progression, motility and invasiveness of tumor cells. We have reported previously that conditioned media from mouse fibroblasts increases the motility of breast cancer cells. Further, we determined that keratinocyte growth factor (KGF) was an active factor from mouse fibroblasts responsible for most of the motility...
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