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Background/ObjectiveObesity increases the risk of cardiovascular disease and diabetic complications in type 1 diabetes. Adipokines, which regulate obesity‐induced inflammation, may contribute to this association. We compared serum adipokines and inflammatory cytokines in obese and lean children with new‐onset autoimmune type 1 diabetes.
Subjects and MethodsWe prospectively studied 32 lean and 18...
BackgroundTreatment with a specific HSP60 epitope in new onset of type 1 diabetes (T1D) patients has been shown to preserve endogenous insulin production. Previously, recognition of pan HLA‐DR‐binding HSP60 epitopes in various autoimmune diseases was found; this study investigated recognition of these epitopes in newly diagnosed T1D patients and correlated findings to the occurrence of a partial remission...
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