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Nimesulide is a nonsteroidal anti‐inflammatory drug (NSAID) and a COX‐2 inhibitor. The native crystal structure of nimesulide (or Form I) has been characterized in the literature by X‐ray powder diffraction (XRPD) lines, whereas full three‐dimensional coordinates are known for a second polymorph (Form II). A detailed structural characterization and phase stability of nimesulide polymorphs were carried...
Crystallization of metastable α and stable γ polymorphs of glycine was carried out from aqueous solution in the presence of ammonia. Pure aqueous solution and solution with lower concentration of ammonia yield α nucleation and solution with a critical concentration of ammonia yield γ nucleation. Variation in the solubility of glycine in double distilled water and pH of the resulting solution due to...
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