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In den vergangenen 10 Jahren hat sich die Bewertung der Rolle von Vitaminen und Spurenelementen in der Primärprävention des Prostatakarzinoms (PCA) gravierend verändert. Es ist bislang nicht gelungen, den Nachweis für die Wirksamkeit einer Einzelsubstanz zu erbringen. Entsprechende Empfehlungen sollten daher heute nicht mehr gegeben werden. Es bleibt sogar zu diskutieren, ob weitere aufwändige Interventionsstudien...
Chemoprevention is prevention of cancer by administering natural or synthetic chemicals. Anti-androgens are among the promising chemopreventive agents for prostate cancer because prostate epithelium is androgen dependent. A National Cancer Institute supported large, randomized, clinical prostate cancer chemoprevention trial has been conducted to test the efficacy of finasteride, an inhibitor of 5-α-reductase,...
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