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A number of studies assessed the association of −589C/T polymorphism in the promoter region of interleukin-4 (IL-4) with asthma in different populations. However, the results were contradictory. A meta-analysis was conducted to investigate the association between polymorphism in the IL-4 and asthma susceptibility.Databases including Pubmed, EMBASE, Wanfang Database, China National Knowledge Infrastructure...
A large number of studies have investigated the correlation between the interleukin (IL)-4 C-589T and C+33T polymorphisms and asthma susceptibility. However, the results are inconsistent. The objective of this study is to explore the association between the IL-4 C-589T and C+33T polymorphisms and asthma risk using meta-analysis.A total of 35 studies (31 concerning C-589T polymorphism and asthma risk...
A number of studies of genetic epidemiology have assessed the association of C-589T (also referred to as C-590T; rs number, 2243250) polymorphisms in the promoter region of interleukin-4 (IL-4) gene with asthma in different populations. However, the results are inconsistent and inconclusive.We performed a meta-analysis of the association between C-589T polymorphisms of IL-4 and asthma with the following...
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