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The long-term effects of zonisamide as monotherapy or adjunctive therapy were investigated in patients with seizure disorders. One hundred twelve adult neurology patients treated with zonisamide were retrospectively identified through a chart review; 90 patients (n=45 monotherapy, n=45 adjunctive therapy) who received zonisamide for ⩾3 months were included in the efficacy-evaluable population, and...
Purpose: To evaluate the long-term clinical usefulness of levetiracetam (LEV, Keppra ( R)1Keppra is a registered trademark of UCB S.A.) as add-on therapy in patients with refractory epilepsy. Methods: Data for all 1422 patients with refractory epilepsy treated with LEV during the development program were analyzed for changes in seizure frequency per week, seizure freedom, and adverse events...
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