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The dementia syndrome is increasing in prevalence throughout the developed world as the population ages. For example, in the United States it is estimated that between 2000 and 2020, the number of people living to 100 years or more will increase by over 200%, and the number of people surviving to 90–95 years will double. Based on these and other epidemiologic data, the prevalence of diseases causing...
Primary progressive aphasia (PPA) is a neurodegenerative disorder with language impairment as the primary feature. Different subtypes have been described and the 3 best characterized are progressive nonfluent aphasia (PNFA), semantic dementia (SD) and logopenic/phonological aphasia (LPA). Of these subtypes, LPA is most commonly associated with Alzheimer's disease (AD) pathology. However, the features...
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