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Vitamin D is involved in skeletal and brain health. Recently, serum 25-hydroxyvitamin D (25OHD) concentration was found to be inversely correlated with intracranial volume in younger adults. Since hypovitaminosis D is most common in older adults, our objective was to determine whether this inverse correlation between 25OHD concentration and intracranial volume also occurred in older adults.Cross-sectional...
Vitamin D insufficiency is associated with brain changes. Our objective was to investigate whether vitamin D insufficiency was associated with a greater volume in mm3 of white matter abnormalities (WMA) in older adults.Seventy-five Caucasian older community-dwellers (mean, 70.9±5.0years; 48%female) received a blood test and brain MRI. The volumes of total white matter (WM) and WMA were measured from...
Vitamin D has multiple functions in the nervous system. Our objective was to systematically review and quantitatively synthesize evidence on the location and nature of brain morphometric changes linked to vitamin D depletion or repletion. A Medline search was conducted in February 2014, without limit of date and language restriction, using the MeSH terms “Vitamin D” OR “Ergocalciferols” combined with...
Studies indicate that diet and vascular calcification may be related to the occurrence of brain lesions, although the importance of dietary calcium and vitamin D has not been investigated. The objective of this study was to test the hypothesis that calcium and vitamin D intakes would be positively associated with brain lesion volumes in elderly individuals with and without late-life depression. A...
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