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In this study, pregnant Wistar dams were exposed to 220 ppm of lead (Pb) in drinking water during gestation and lactation. The response to the locomotor-stimulating effects of 0.5 mg/kg of amphetamine (AMPH) was evaluated in 35-day-old male offspring. The results demonstrated that developmental Pb exposure induced no differences in the response to the drug, although an increase in locomotor activity...
The effects of neonatal lead (Pb) exposure on ability to endure stress and on the onset of sexual maturity were investigated using rats. Sprague-Dawley dams (n = 17/treatment) were treated with or without lead acetate (0.3%) in drinking water from parturition until postnatal day (PND) 21, at which time the pups were weaned. A set of sex-balanced pairs of pups (24 male and 24 females/treatment) from...
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