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Nanomaterials‐Mediated Gene Editing for Cancer Therapy
In article number 2300665, Yu Tao, Mingqiang Li, Jianxun Ding, and co‐workers present a comprehensive overview of the revolutionary potential of applying nanomaterial‐enhanced CRISPR/Cas9 gene editing systems for cancer therapy. The rationally engineered nanoformulations exhibit a pronounced enhancement of the safety, efficiency, and specificity...
Clustered regularly interspaced short palindromic repeats/associated protein 9 (CRISPR/Cas9) gene‐editing technology shows promise for manipulating single or multiple tumor‐associated genes and engineering immune cells to treat cancers. Currently, most gene‐editing strategies rely on viral delivery; yet, while being efficient, many limitations, mainly from safety and packaging capacity considerations,...