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Das hepatozelluläre Karzinom stellt eine der weltweit wichtigsten Tumorentitäten dar. Die große Mehrzahl der Erkrankungen in Deutschland geht auf eine chronische Leberschädigung (Alkohol, Virushepatitis u. a.) zurück, die zur Entwicklung einer Leberzirrhose und schließlich zum hepatozellulären Karzinom führt. Während das Verständnis der pathophysiologischen Grundlagen der Entstehung des hepatozellulären...
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